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Tumor-Penetrating iRGD Peptide Inhibits Metastasis
Sugahara KN, Braun GB, de Mendoza TH, Kotamraju VR, French RP, Lowy AM, Teesalu T, Ruoslahti E.
Mol Cancer Ther. 2015 Jan;14(1):120-8. doi: 10.1158/1535-7163.MCT-14-0366. Epub 2014 Nov 12.
Reprogramming Human Retinal Pigmented Epithelial Cells to Neurons Using Recombinant Proteins
Hu Q, Chen R, Teesalu T, Ruoslahti E, Clegg DO.
Stem Cells Transl Med. 2014 Oct 8. pii: sctm.2014-0038.
Etchable plasmonic nanoparticle probes to image and quantify cellular internalization
Braun GB, Friman T, Pang HB, Pallaoro A, de Mendoza TH, Willmore AM, Kotamraju VR, Mann AP, She ZG, Sugahara KN, Reich NO, Teesalu T, Ruoslahti E.
Nat Mater. 2014 Jun 8. doi: 10.1038/nmat3982.
A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity
Hong-Bo Pang, Gary B. Braun, Zhi-Gang She, Venkata R. Kotamraju, Kazuki N. Sugahara, Tambet Teesalu, Erkki Ruoslahti
J Control Release. 2014 Feb 10;175:48-53. doi: 10.1016/j.jconrel.2013.12.006. Epub 2013 Dec 15.
Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies
Sánchez-Martín D, Martínez-Torrecuadrada J, Teesalu T, Sugahara KN, Alvarez-Cienfuegos A, Ximénez-Embún P, Fernández-Periáñez R, Martín MT, Molina-Privado I, Ruppen-Cañás I, Blanco-Toribio A, Cañamero M, Cuesta AM, Compte M, Kremer L, Bellas C, Alonso-Camino V, Guijarro-Muñoz I, Sanz L, Ruoslahti E, Alvarez-Vallina L
Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13791-6. doi: 10.1073/pnas.1300013110. Epub 2013 Aug 5
Tumor-penetrating peptides
Teesalu T, Sugahara KN, Ruoslahti E
Front. Oncol., 27 August 2013 | doi: 10.3389/fonc.2013.00216
Sequence dependence of C-end rule peptides in binding and activation of neuropilin-1 receptor
Zanuy D, Kotla R, Nussinov R, Teesalu T, Sugahara KN, Alemán C, Haspel N.
J Struct Biol. 2013 Feb 24. doi:pii: S1047-8477(13)00043-9. 10.1016/j.jsb.2013.02.006. [Epub ahead of print]
The non-peptidic part determines the internalization mechanism and intracellular trafficking of peptide amphiphiles
Missirlis D, Teesalu T, Black M, Tirrell M.
PLoS One. 2013;8(1):e54611. doi: 10.1371/journal.pone.0054611. Epub 2013 Jan 17.
Application of a proapoptotic peptide to intratumorally spreading cancer therapy
Chen R, Braun GB, Luo X, Sugahara KN, Teesalu T, Ruoslahti E.
Cancer Res. 2013 Feb 15;73(4):1352-61. doi: 10.1158/0008-5472.CAN-12-1979. Epub 2012 Dec 17.
De novo design of a tumor-penetrating peptide
Alberici L, Roth L, Sugahara KN, Agemy L, Kotamraju VR, Teesalu T, Bordignon C, Traversari C, Rizzardi GP, Ruoslahti E.
Cancer Res. 2013 Jan 15;73(2):804-12. doi: 10.1158/0008-5472.CAN-12-1668. Epub 2012 Nov 14.
Mapping of vascular ZIP codes by phage display
Teesalu T, Sugahara KN, Ruoslahti E.
Methods Enzymol. 2012;503:35-56. doi: 10.1016/B978-0-12-396962-0.00002-1.
