Ali Baba and fourty thieves a.k.a 41 T7 bacteriophages amplifying on the E. coli agar plate.
Author: Tarmo Mölder, MSc
U87 cell line spheroids taking up RPARPAR-AgNPs (red)
Technology: Confocal microscopy 20x
Author: Kadri Toome, MSc
In vivo imaging of a mouse bearing luciferase-expressing MKN-45 gastric carcinoma.
Left: luminiscence of the gastric tumor. Right: fluorescence of polymeric vesicles homing to the tumor.
Images were acquired using ART OPTIX MX3 imaging system.
Authors: Lorena Simón Gracia, PhD and Pablo Scodeller, PhD
SKOV3 ovarian cancer cells
Technical information: PS-Rho-iRGD-FAM
Polymersomes-Red
iRGD peptide -Green
NRP-1-Purple
Nuclei-Blue
Author: Hedi Hunt, MSc
1st of March Maarja Haugas joined the CancerBiology Lab as a neurobiology specialist
At the beginning of March a new member Maarja Haugas joined with the Lab of Cancer Biology. After ten years in Finland at the University of Helsinki, where she defended a PhD degree in developmental biology and veterinary anatomy in 2011 and continued as a postdoctoral researcher in developmental neurobiology, she has returned to beloved University of Tartu. She has background in molecular and developmental biology and in neuroscience, as well as know-how in histology.
An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability
Pang HB, Braun GB, Friman T, Aza-Blanc P, Ruidiaz ME, Sugahara KN, Teesalu T, Ruoslahti E.
Nat Commun. 2014 Oct 3;5:4904. doi: 10.1038/ncomms5904.
Pablo Scodeller comes aboard LCB to bridge nanotechnology to tumor biology
Starting from 1st of February a new lab member has joined us. Pablo David Scodeller is from Argentina and he concluded his PhD studies in the University of Buenos Aires under the supervision of Dr. Ernesto Calvo. He then went on to work in the 'Chemistry of Nanomaterials' group led by Dr. Galo Soler Illia of Buenos Aires, under CONICET fellowship. For the last two years he's been working in the 'Vascular Mapping Laboratory' of Dr. Erkki Ruoslahti at Sanford-Burnham Medical research Institute, in La Jolla, USA. His main research interests are: Nanomedicine, Tumor microenvironment, drug penetration, drug delivery, adjuvants of oncolytic drugs. Phage display in vivo and in vitro. Neurodegenerative diseases and brain injuries. His main hobbies include: cogitations over beer, tango music, attending milongas, and the study of the Buenos Aires jargon called Lunfardo .
Co-culture of NRP1 (green) expressing PPC1 cells along with M21 cells; both cell lines express p32 (white), RPARPAR-AgNPs (red) are taken up by PPC1 cells.
Technical information: Confocal microscopy 63x.
Author: Anne-Mari Anton Willmore, Lorena Simon Gracia
